Search Results - Animal/Veterinary

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A Recombinant Subunit Vaccine With Enhanced Immunity Against Porcine Epidemic Diarrhea Virus (PEDV)
Since its emergence in the United States in 2013, porcine epidemic diarrhea virus (PEDV) has devastated the U.S. swine industry causing immense economic losses. This invention report the creation of a subunit vaccine that can also enhance T cell immunity against PEDV, and thus such a vaccine will have significant commerical value to the swine industry...
Published: 8/24/2017   |   Inventor(s): Sakthivel Subramaniam, Yao-Wei Huang, Xiang-Jin Meng
Category(s): Animal/Veterinary, Biomedical
Adipose Derived Stem Cell Therapy for Animals
Adipose-derived stem cells (ASCs) are easily isolated and grow rapidly, allowing treatment within 10 days. A same-day adipose cell therapy involves tissue digestion and collection of the cell mixture-the stromal vascular fraction (SVF). Platelet rich plasma (PRP) has been used as a vehicle for stem cell therapy, providing growth factors and scaffold...
Published: 9/21/2015   |   Inventor(s): Jennifer Barrett
Category(s): Animal/Veterinary
Novel MLV and Subunit Vaccines Created by DNA Shuffling Against Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)
Porcine reproductive and respiratory syndrome virus (PRRSV) is arguably the most economically important swine pathogen worldwide. The current available vaccines were generally effective against homologous strains but were less effective or ineffective against heterologous strains. Given the degree of genetic diversity observed among PRRSV strains, it...
Published: 7/15/2015   |   Inventor(s): Yanyan Ni, Yao-Wei Huang, Xiang-Jin Meng
Category(s): Animal/Veterinary
Novel Methylerythritol Phosphate Pathway Inhibitors
The apicoplast is essential to the malaria parasite and its main function during asexual blood stages is to provide the isoprenoid precursor isopentenyl diphosphate (MEP) pathway. Without IPP, the parasite cannot synthesize isoprenoids; this IPP deficit is cytocidal and may also reduce the ability of the parasite to invade host cells. Since humans...
Published: 10/29/2014   |   Inventor(s): Paul Carlier, Maria Belen Cassera, Emilio Merino, Zhong-Ke Yao
Category(s): Medical, Agriculture, Animal/Veterinary, Biomedical, Therapeutic
Methods For Therapeutic Targeting Cancer Stem Cells
Patients with the brain cancer glioblastoma have about a year to live once diagnosed. Glioblastoma kills quickly as it grows aggressively and patients develop resistance to the anti-cancer drug temozolomide. Studies by a team at Virginia Tech indicate that a protein called Cx43 may hold the key to temozolomide resistance. Our researchers have found...
Published: 2/6/2014   |   Inventor(s): Zhi Sheng, Robert Gourdie
Category(s): Medical, Biology, Animal/Veterinary, Biomedical, Biotechnology, Therapeutic, Drug Delivery, Drug Discovery, Drug Screening, Gene Therapy
Method to Protect Plants and Animals against Pathogen Infection by Blocking Entry of Virulence Proteins
The invention includes methods and compositions that prevent pathogen virulence proteins from entering into plant or animal cells, including humans, thus providing a novel mechanism for protection from infection.
Published: 9/3/2012   |   Inventor(s): Brett Tyler, Daolong Dou, Shiv Kale, Biao Gu
Keywords(s): Medical/Therapeutic
Category(s): Agriculture, Animal/Veterinary, Biomedical
Avian Hepatitis E Virus (avian HEV) and Its Uses Thereof
Novel avian hepatitis E virus, immunogenic compositions, diagnostic reagents, vaccines and methods of detection or protecting against avian hepatitis-splenomegaly syndrome and mammalian Hepatitis E. US Patents: 7,005,130 - Issued February 26, 2006 7,582,303 - Issued September 1, 2009 7,842,298 -...
Published: 9/3/2012   |   Inventor(s): Xiang-Jin Meng, Gholamreza Haqshenas, Fang-Fang Huang
Keywords(s): Animal Health, Pharmaceuticals & Biotechnology
Category(s): Animal/Veterinary
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