Search Results - animal%2fveterinary

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Horse Distal Limb Ultrasound Simulator
THE CHALLENGE Lameness is a term typically used to describe a change in a horse gait in response to pain in one of the distal limbs. Sometimes, lameness is obvious manifesting as a noticeable limp; other cases have more subtle signs and can be harder to detect. Successfully resolving lameness cases due to distal limb problems depends mainly on the...
Published: 8/18/2022   |   Inventor(s): Fawzy Elnady, Yusuf Elnady, Lauren Trager Burns
Category(s): Animal/Veterinary
Canine Otoscopy Training Model
THE CHALLENGE Otoscopy examinations, which examine the structures of the ear, are vital for veterinary health. Understanding and properly performing this exam on cats and dogs is a skill that requires extra practice. Movement of live animals increases the difficulty of the exam, so studying the process and beginning practice on a more manageable model...
Published: 9/9/2021   |   Inventor(s): Fawzy Elnady, Heng Tham
Category(s): Animal/Veterinary
ColicAlert Equine Wearable Heart Rate Monitor
THE CHALLENGE The vitality of the equine industry is damaged by a persistent, prevalent, and difficult-to-predict metabolic disease called colic. Colic is estimated to result in $115 million in losses annually. A major challenge in treating colic is that horses often fail to show conclusive clinical symptoms until the condition has progressed to the...
Published: 7/29/2021   |   Inventor(s): Caroline Leeth, Robin White
Category(s): Animal/Veterinary, Devices
A Recombinant Subunit Vaccine With Enhanced Immunity Against Porcine Epidemic Diarrhea Virus (PEDV)
Since its emergence in the United States in 2013, porcine epidemic diarrhea virus (PEDV) has devastated the U.S. swine industry causing immense economic losses. This invention report the creation of a subunit vaccine that can also enhance T cell immunity against PEDV, and thus such a vaccine will have significant commerical value to the swine industry...
Published: 11/27/2017   |   Inventor(s): Sakthivel Subramaniam, Yao-Wei Huang, Xiang-Jin Meng
Category(s): Animal/Veterinary, Biomedical
Novel MLV and Subunit Vaccines Created by DNA Shuffling Against Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)
Porcine reproductive and respiratory syndrome virus (PRRSV) is arguably the most economically important swine pathogen worldwide. The current available vaccines were generally effective against homologous strains but were less effective or ineffective against heterologous strains. Given the degree of genetic diversity observed among PRRSV strains, it...
Published: 1/5/2023   |   Inventor(s): Yanyan Ni, Yao-Wei Huang, Xiang-Jin Meng
Category(s): Animal/Veterinary
Novel Methylerythritol Phosphate Pathway Inhibitors
The apicoplast is essential to the malaria parasite and its main function during asexual blood stages is to provide the isoprenoid precursor isopentenyl diphosphate (MEP) pathway. Without IPP, the parasite cannot synthesize isoprenoids; this IPP deficit is cytocidal and may also reduce the ability of the parasite to invade host cells. Since humans...
Published: 11/27/2017   |   Inventor(s): Paul Carlier, Maria Belen Cassera, Emilio Merino, Zhong-Ke Yao
Category(s): Medical, Agriculture, Animal/Veterinary, Biomedical, Therapeutic
Methods For Therapeutic Targeting Cancer Stem Cells
Patients with the brain cancer glioblastoma have about a year to live once diagnosed. Glioblastoma kills quickly as it grows aggressively and patients develop resistance to the anti-cancer drug temozolomide. Studies by a team at Virginia Tech indicate that a protein called Cx43 may hold the key to temozolomide resistance. Our researchers have found...
Published: 11/27/2017   |   Inventor(s): Zhi Sheng, Robert Gourdie
Category(s): Medical, Biology, Animal/Veterinary, Biomedical, Biotechnology, Therapeutic, Drug Delivery, Drug Discovery, Drug Screening, Gene Therapy
Method to Protect Plants and Animals against Pathogen Infection by Blocking Entry of Virulence Proteins
The invention includes methods and compositions that prevent pathogen virulence proteins from entering into plant or animal cells, including humans, thus providing a novel mechanism for protection from infection.
Published: 11/27/2017   |   Inventor(s): Brett Tyler, Daolong Dou, Shiv Kale, Biao Gu
Keywords(s): Medical/Therapeutic
Category(s): Agriculture, Animal/Veterinary, Biomedical
Avian Hepatitis E Virus (avian HEV) and Its Uses Thereof
Novel avian hepatitis E virus, immunogenic compositions, diagnostic reagents, vaccines and methods of detection or protecting against avian hepatitis-splenomegaly syndrome and mammalian Hepatitis E. US Patents: 7,005,130 - Issued February 26, 2006 7,582,303 - Issued September 1, 2009 7,842,298 -...
Published: 11/27/2017   |   Inventor(s): Xiang-Jin Meng, Gholamreza Haqshenas, Fang-Fang Huang
Keywords(s): Animal Health, Pharmaceuticals & Biotechnology
Category(s): Animal/Veterinary