Search Results - biomedical

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A Recombinant Subunit Vaccine With Enhanced Immunity Against Porcine Epidemic Diarrhea Virus (PEDV)
Since its emergence in the United States in 2013, porcine epidemic diarrhea virus (PEDV) has devastated the U.S. swine industry causing immense economic losses. This invention report the creation of a subunit vaccine that can also enhance T cell immunity against PEDV, and thus such a vaccine will have significant commerical value to the swine indus...
Published: 8/24/2017   |   Inventor(s): Sakthivel Subramaniam, Yao-Wei Huang, Xiang-Jin Meng
Category(s): Animal/Veterinary, Biomedical
Cyclic gamma-Amino Acids and Peptoid Foldamers
Isonipecotic acid provides a stable scaffold with the potential for useful functionalization. Changing the side chains at the β- or γ-positions in the piperidyl ring will tune a peptide towards its biological target or catalytic function. Modifications at these positions is expected to have little effect on the chair conformation adopted...
Published: 6/13/2017   |   Inventor(s): Jatinder Josan, Robert Grams
Category(s): Medical, Biomedical, Biology, Biotechnology, Chemicals, Drug Delivery, Drug Discovery
Structure Illuminated Color X-ray Phase Imaging for Breast Cancer Screening
One in every nine women is expected to develop breast cancer in her life. Current mainstream screening technology is the mammography. Mammography suffers from a range of problems including low signal level, poor contrast, and radiation dose. It leads to severe over-diagnostic problems. In contrast, our breast cancer screening system with color X-ra...
Published: 6/13/2017   |   Inventor(s): Guohua Cao
Category(s): Biomedical, Devices, Diagnostic
Tissue-Conforming Microfluidic Devices
A device that establishes fluidic interfaces with biological tissue for the purposes of isolating biological information and delivering therapeutic material to the biological tissue.
Published: 6/8/2017   |   Inventor(s): Blake Johnson, John Robertson, Manjot Singh, Yuxin Tong, Alexander Haring
Category(s): Medical, Biomedical, Biotechnology, Devices
Method of Scatter Correction in Multi-source Computed Tomography
This invention includes three x-ray scatter correction methods dedicated to the multi-source computed tomography (CT). The first one is stationary beam-stopper-arrays based method, and enables the online correction of both forward and cross scatter signals. The second one is x-ray source trigger sequence based method, and enables cross scatter corr...
Published: 4/3/2017   |   Inventor(s): Guohua Cao, Hao Gong
Category(s): Biomedical, Engineering
Enzymatic Biotransformation of Sucrose to Myo-Inositol Via Non-Natural Pathways and Thereof
We constructed in vitro enzymatic pathways that can convert sucrose to myo-inositol and fructose. Myo-inositol is vitamin V8, which has been widely used in the pharmaceutical, drink, food, feed, and cosmetic industries. Without product separation, a mixture of inositol and fructose will be a perfect functional sweetener, which may be directly added...
Published: 3/3/2017   |   Inventor(s): Yi-Heng Percival Zhang, Chun You, Chao Zhong
Category(s): Biomedical, Biotechnology
Ultrafast Micro-CT for Imaging Free-Moving Animals
All current small animal imaging requires some form of anesthetization. The anesthetization not only may interfere with the subject's pathophysiology under study, and also is a costive and skill-demanding process. The current invention will eliminate the need for administration of anesthesia during small animal micro-CT imaging experiments, thus le...
Published: 2/6/2017   |   Inventor(s): Guohua Cao
Keywords(s): Biotechnology/Imaging, Imaging, Medical/Imaging
Category(s): Biomedical, Devices, Diagnostic, Drug Delivery, Drug Screening, Gene Therapy
Tapping into FGFBP1 to Treat a Variety of Pathological Conditions that Affect Skeletal Muscles and Spinal Cord
This firbroblast growth factor binding protein 1 (FGFBP1) and small peptides that mimic its function have the potential of treating a wide-range of conditions that affect skeletal muscles and motor neurons. Because FGFBP1 is significantly decreased prior to the onset of amyotrophic lateral sclerosis in skeletal muscles, it also serves as a biomarke...
Published: 12/9/2016   |   Inventor(s): Gregorio Valdez
Category(s): Biomedical
Novel Compositions and Methods for Heart Ischemia Reperfusion Injury
Ischemic heart disease is the biggest cause of death and disease among men worldwide and the second biggest killer of women - just behind ischemic stroke. We have developed a drug that can be given after an ischemic event such as a heart attack - i.e., myocardial infarction. This drug preserves heart muscle, reduces scarring and prevents the progre...
Published: 11/18/2016   |   Inventor(s): Robert Gourdie, Linda Jourdan, Jingbo Jiang
Category(s): Biomedical
Passive Anti-Frosting Surface Comprised of Periodic Micro-Grooves Containing Sacrificial Ice Stripes
To date, no surface technology exists that can passively suppress the growth of frost under chilled and humid conditions. Active techniques, such as applying heat or antifreeze chemicals to the surface, are energetically costly and/or environmentally harmful. The closest thing to a passive anti-frosting technology is the sprinkling of salt over a s...
Published: 8/8/2016   |   Inventor(s): Jonathan Boreyko, Saurabh Nath, Caitlin Bisbano, Grady Iliff
Category(s): Biomedical, Engineering
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