Search Results - joseph+merola

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Highly Modifiable Anti-Viral Scaffold
THE CHALLENGE New infectious diseases for which there are no effective pharmaceuticals available are a significant threat to the global population. Infections that are more difficult to treat, such as Mycobacterium tuberculosis (TB), methicillin-resistant Staphylococcus aureus (MRSA), and SARS-CoV-2 (causative agent of COVID-19) present a unique challenge....
Published: 9/29/2021   |   Inventor(s): Joseph Merola, James Weger, Christine Duchane, Christina Chuong, Chad Bernier
Category(s): Biomedical
Acetylacetonate and Related Complexes of Cobalt, Rhodium, Iridium and Ruthenium Piano Stool Compunds as Anti-Microbial Agents
A completely new platform for anti-microbials that are effective against various antibiotic-resistant diseases has been developed. The platform is highly customizable to target different pathogens. Specific examples of compounds effective against mycobacteria and MRSA have been synthesized and tested in vitro.
Published: 9/21/2015   |   Inventor(s): Joseph Merola, Joseph Falkinham, Christine Duchane, George Karpin
Category(s): Medical
Anti-Microbial Properties of Amino Acid Complexes of the Later Transition Metals
Antibiotic resistant strains of bacteria are more frequently reported and present an immediate and severe danger to many people. New manners of fighting these infections are being sought, with several particularly promising compounds being developed at Virginia Tech. The creation of transition metal complexes with effective anti-microbial properties...
Published: 9/5/2012   |   Inventor(s): Joseph Merola
Category(s): Medical, Chemicals, Materials, Biomedical, Therapeutic