Search Results - pharmaceuticals & biotechnology

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Novel Small-Molecule Antidepressants
These potential antidepressant compounds have a novel mechanism of action – blockade of transporters for the neurotransmitters norepinephrine, serotonin, and dopamine. This novel “triple reuptake blockade” approach holds promise for a more effective and rapidly-acting antidepressant.
Published: 4/1/2014   |   Inventor(s): Paul Carlier, Elliott Richelson
Keywords(s): Pharmaceuticals & Biotechnology
Category(s): Medical, Biotechnology
A Drug and Vaccine Target for Malaria
A novel protein, HDP, from Plasmodium and related parasites is a target for therapeutic intervention in diseases caused by the malarial parasites. US Patent 7,438,916
Published: 9/11/2012   |   Inventor(s): Dharmendar Rathore, Dewal Jani, Rana Nagarkatti
Keywords(s): Pharmaceuticals & Biotechnology
Category(s): Drug Discovery
Drug Targets for Fungal-Associated Respiratory Disorders
Proteins from the fungus Alternaria have importance in the pathogenesis of some chronic respiratory allergies and disorders. This technology identifies fungal proteins that are critical for the onset of these diseases and are potential drug targets. US Patent 7,662,400 US Patent 7,887,820 US Patent 7,972,611
Published: 9/5/2012   |   Inventor(s): Christopher Lawrence
Keywords(s): Pharmaceuticals & Biotechnology
Category(s): Drug Screening
Microfluidic Device with MALDI-MS Detection for Complex Sample Processing
The present invention provides a microfluidic device and method for facilitating on-chip complex sample processing and detection. In general, the device comprises at least a separation channel of a separation system, an interface, and an array of microreservoirs disposed within the same chip. The interface is configured to orthogonally transfer sep...
Published: 9/3/2012   |   Inventor(s): Iuliana Lazar
Keywords(s): Biotechnology, Medical Diagnostics, New Portfolio, Pharmaceuticals & Biotechnology
Category(s): Proteomics
Conformationally-Constrained Paclitaxels as Anticancer Agents
This technology is a new class of paclitaxel analogs. The general structure includes a bridging bond that constrains the 3-D structure of the compound. The resulting conformation of the paclitaxel analog promotes binding to and polymerization of tubulin. US Patent 7,312,240
Published: 9/3/2012   |   Inventor(s): David Kingston, Thota Ganesh, James Snyder, Ami Lakdawala, Susan Bane
Keywords(s): Pharmaceuticals & Biotechnology
Category(s): Therapeutic, Biomedical
Oral Treatment of Hemophilia
One of the challenges in treating hemophilia is that patients frequently develop antibodies to the protein(s) used to correct clotting factor deficiencies. This patented technology is a method for oral administration of a clotting factor to induce immunologic tolerance while providing therapeutic levels of clotting factor replacement. The method c...
Published: 9/3/2012   |   Inventor(s): William Velander, Oral Alpan, Tirumalaj Kamala, Polly Matzinger
Keywords(s): Pharmaceuticals & Biotechnology
Category(s): Drug Delivery
Avian Hepatitis E Virus (avian HEV) and Its Uses Thereof
Novel avian hepatitis E virus, immunogenic compositions, diagnostic reagents, vaccines and methods of detection or protecting against avian hepatitis-splenomegaly syndrome and mammalian Hepatitis E. US Patents: 7,005,130 - Issued February 26, 2006 7,582,303 - Issued September 1, 2009 7,842,298 -...
Published: 9/3/2012   |   Inventor(s): Xiang-Jin Meng, Gholamreza Haqshenas, Fang-Fang Huang
Keywords(s): Animal Health, Pharmaceuticals & Biotechnology
Category(s): Animal/Veterinary
Antimicrobial Compounds to Inhibit Plant Diseases
The technology is a group of naturally-occurring peptides that inhibit growth of many bacteria, yeast, fungi, protozoa, and algae that cause disease in plants. See related technology 10-060.
Published: 8/6/2012   |   Inventor(s): Cody Cain, Lester Casida, Joseph Falkinham
Keywords(s): Pharmaceuticals & Biotechnology
Category(s): Agriculture
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