Search Results - robert+gourdie

3 Results Sort By:
Novel Compositions and Methods for Heart Ischemia Reperfusion Injury
Ischemic heart disease is the biggest cause of death and disease among men worldwide and the second biggest killer of women - just behind ischemic stroke. We have developed a drug that can be given after an ischemic event such as a heart attack - i.e., myocardial infarction. This drug preserves heart muscle, reduces scarring and prevents the progression...
Published: 11/18/2016   |   Inventor(s): Robert Gourdie, Linda Jourdan, Jingbo Jiang
Category(s): Biomedical
Novel Compositions and Methods for Hemichannel Inhibition
The compositions GaPS and methods for their use are provided. GaPS can have potent inhibitory and clinically useful effects on gap junction and structurally related hemichannels. Inhibiting these channels has proven to have clinical benefits in the injury response and for numerous diseases, including in reducing excess inflammation, scarring and fibrosis,...
Published: 7/2/2015   |   Inventor(s): Robert Gourdie, Linda Jourdan
Category(s): Medical, Biology, Biotechnology, Biomedical, Chemicals, Drug Delivery
Methods For Therapeutic Targeting Cancer Stem Cells
Patients with the brain cancer glioblastoma have about a year to live once diagnosed. Glioblastoma kills quickly as it grows aggressively and patients develop resistance to the anti-cancer drug temozolomide. Studies by a team at Virginia Tech indicate that a protein called Cx43 may hold the key to temozolomide resistance. Our researchers have found...
Published: 2/6/2014   |   Inventor(s): Zhi Sheng, Robert Gourdie
Category(s): Medical, Biology, Animal/Veterinary, Biomedical, Biotechnology, Therapeutic, Drug Delivery, Drug Discovery, Drug Screening, Gene Therapy