Search Results - david+kingston

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Novel Electrolyte Formulation to Enhance Cardiac Function
­THE CHALLENGE There are over 350,000 out-of-hospital cardiac arrests each year, with each patient seen by EMS receiving a liter of crystalloid solution (usually 0.9% saline). Only about two thirds of those patients have a pulse return; the remainder die from the condition called pulseless electrical activity (PEA) or electromechanical disassociation....
Published: 4/22/2022   |   Inventor(s): Steven Poelzing, David King
Category(s): Biomedical
Constituents of Morning Glory as Anticancer Agents
Ipomoeassin compounds derived from morning glory plant material (especially Ipomoea sp. from Suriname) are useful as anti-cancer agents. The novel compounds also are useful for treating neurodegenerative disorders (such as Alzheimer's disease) in human patients.
Published: 9/3/2012   |   Inventor(s): David Kingston, Shugeng Cao
Category(s): Biomedical
Conformationally-Constrained Paclitaxels as Anticancer Agents
This technology is a new class of paclitaxel analogs. The general structure includes a bridging bond that constrains the 3-D structure of the compound. The resulting conformation of the paclitaxel analog promotes binding to and polymerization of tubulin. US Patent 7,312,240
Published: 9/3/2012   |   Inventor(s): David Kingston, Thota Ganesh, James Snyder, Ami Lakdawala, Susan Bane
Keywords(s): Pharmaceuticals & Biotechnology
Category(s): Therapeutic, Biomedical