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Novel Mosquito-Targeting Insecticide
ABOUT THE TECHNOLOGY
Globally in 2022, there were an estimated 249 million malaria cases and 608,000 malaria deaths in 85 countries. Malaria has been and continues to be a prominent health concern all over the world. In some areas, the method of defense against the vector, Anopheles gambiae, is profoundly limited. For example, many of those in sub-Saharan...
Published: 1/16/2024
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Inventor(s): Joshua Hartsel, Ming Ma, Troy Anderson, Ranginee Choudhury, Paul Carlier, Jeffrey Bloomquist, Sally Paulson, Eric Wong
Keywords(s): Agriculture/Pest Control
Category(s): Technology Classifications > Chemicals/Materials, Technology Classifications > Biomedical, Technology Classifications > Pharmacology and Therapeutics
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Formulation of Iron Oxide Nanoparticle Suspensions for FUS/MRI Applications
Focused ultrasound combined with magnetic resonance imaging (FUS/MRI) is a promising approach for noninvasive therapy that requires precise imaging of tissue using MRI to guide the FUS process. The MRI suffers from interference from water baths commonly used to transmit the focused ultrasound waves from a transmitter to the tissue. In this work, iron...
Published: 12/20/2023
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Inventor(s): Richey Davis, Austin Fergusson, Eli Vlaisavljevich, Connor Edsall, Craig Meyer, Steven Allen
Keywords(s):
Category(s): Technology Classifications > Biomedical, Technology Classifications > Biotechnology
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An Assistive Robotic Exoskeleton Glove Designed for Patients with
Brachial Plexus Injuries
THE CHALLENGE
Exoskeleton gloves have proven to be invaluable in post-surgery therapy for patients with Brachial Plexus Injuries, countering hand muscle atrophy through controlled and assisted movements. While many rehab gloves target stroke recovery, they lack the desired Human-Machine Interface and struggle to find the right balance between performance...
Published: 11/21/2023
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Inventor(s): Pinhas Ben-Tzvi, Bijo Sebastian, Eric Refour
Keywords(s):
Category(s): Technology Classifications > Engineering, Technology Classifications > Biomedical, Technology Classifications > Biotechnology, Technology Classifications > Electronics, Technology Classifications > Medical Devices, Technology Classifications > Robotics
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Nanoparticle-based Nicotine Nanovaccine
THE CHALLENGE:
Tobacco smoking is one of the largest public health threats the world has ever faced and results in over seven million deaths annually world wide. Smoking cessation is a difficult and largely unsuccessful undertaking; only 3-5% of unassisted smokers are able to remain abstinent for more than six months, and the use of pharmacological...
Published: 11/7/2023
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Inventor(s): Chenming (mike) Zhang, Zongmin Zhao
Keywords(s):
Category(s): Technology Classifications > Biomedical, Technology Classifications > Biotechnology, Technology Classifications > Pharmacology and Therapeutics
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Novel Electrolyte Formulation to Enhance Cardiac
Function
THE CHALLENGE
There are over 350,000 out-of-hospital cardiac arrests each year, with each patient seen by EMS receiving a liter of crystalloid solution (usually 0.9% saline). Only about two thirds of those patients have a pulse return; the remainder die from the condition called pulseless electrical activity (PEA) or electromechanical disassociation....
Published: 11/7/2023
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Inventor(s): Steven Poelzing, David King
Keywords(s):
Category(s): Technology Classifications > Biomedical, Technology Classifications > Pharmacology and Therapeutics
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New process for selective polysaccharide derivative oxidation
THE CHALLENGE
Aqueous solubility and controllable release are essential for bioactive compounds. In the case of oral drug delivery, poor aqueous solubility of a drug can lead to low bioavailability. For poorly bioavailable drugs, higher doses are required to achieve a therapeutic concentration in systemic circulation. This can in turn have negative...
Published: 11/7/2023
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Inventor(s): Kevin Edgar, Brittany Nichols, Ann Norris, Laura Mosquera-Giraldo, Lynne Taylor, Junyi Chen, Charles Frazier, Benjamin Adams
Keywords(s):
Category(s): Technology Classifications > Chemicals/Materials, Technology Classifications > Biotechnology, Technology Classifications, Technology Classifications > Biomedical, Technology Classifications > Pharmacology and Therapeutics
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Residual Glioblastoma and Glioma Cell Capture
THE CHALLENGE
Physical removal of tumors in most cases cannot eradicate all the cancerous cells in the affected area. The cells that are left behind are known as residual tumor cells due to their inability to be removed. Some of these residual cells are also resistant to chemotherapy which make them particularly threatening as this is the primary method...
Published: 1/31/2024
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Inventor(s): Zerin Khan, Scott Verbridge, Timothy Long, Eli Vlaisavljevich
Keywords(s):
Category(s): Technology Classifications > Biomedical, Technology Classifications, Technology Classifications > Pharmacology and Therapeutics
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Multiresonant Plasmonic Meshes for Bio-interfaced
Sensing and Actuation
THE CHALLENGE
Mesh plasmonic devices have the potential to combine the biocompatibility of polymeric meshes with the capabilities of plasmonic nanostructures to enhance nanoscale light-matter interactions for bio-interfaced optical sensing and actuation. However, scalable integration of uniformly structured plasmonic hotspot arrays with polymeric meshes...
Published: 2/1/2024
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Inventor(s): Aditya Garg, Wei Zhou, Peter Vikesland
Keywords(s):
Category(s): Technology Classifications > Biomedical, Technology Classifications, Technology Classifications > Biotechnology, Technology Classifications > Chemicals/Materials
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Programmed Innate Leukocytes as Potent Therapeutic Agents to Treat Atherosclerosis and Stroke
This invention discloses a novel strategy to reprogram either allogenic or heterologous peripheral blood neutrophils and/or monocytes with a selective compound in vitro, into a homeostatic state that is conducive for healing of coronary heart disease and/or stroke. Reprogrammed monocytes and/or neutrophils can be used through i.v. injection into human...
Published: 1/31/2024
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Inventor(s): Liwu Li, Shuo Geng, Yao Zhang
Keywords(s):
Category(s): Technology Classifications > Biomedical
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Therapeutic Applications to Modulate BRCA1 in Cancer Cells
Physical properties of BRCA1 make in amenable to unconventional treatment options that interfere with or modify the protein to control its function in cells. In the case of healthy individuals therapeutic applications to stabilize the BRCA1 protein may be beneficial as a preventative measure -- either before or following primary interventions. In the...
Published: 1/31/2024
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Inventor(s): Deborah Kelly, Yanping Liang, William Dearnaley
Keywords(s):
Category(s): Technology Classifications, Technology Classifications > Biomedical, Technology Classifications > Biotechnology
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