Search Results - rafael+davalos

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Method of Reducing Thermal Damage During Electroporation-Based Treatments and Therapies Using Minimal Energy Electrical Pulses
Electroporation is a process by which intense electric fields generate nano-scale defects within the cell membrane. These defects allow molecular exchange between the cell interior and the extracellular environment. We have developed a method by which a minimal amount of energy may be delivered to a cell suspension that will render the cells permeable...
Published: 2/6/2017   |   Inventor(s): Daniel Sweeney, Rafael Davalos, James Weaver, T.r. Gowrishankar, Reuben Seongwoo Son
Category(s): Medical
Bioprinting of 3D (Three Dimensional) Bacterial Cellulose (BC) Scaffold for Tissue Engineering
A novel BC fermentation technique for controlling 3D shape, thickness and architecture of the entangled cellulose nano-fibril network is presented. The resultant nano-cellulose based structures are useful as biomedical implants and devices, are useful for tissue engineering and regenerative medicine, and for health care products. More particularly,...
Published: 10/23/2015   |   Inventor(s): Paul Gatenholm, Henrik Backdahl, Theodore Jon Tzavaras, Rafael Davalos, Michael Sano
Keywords(s): Medical/Biofabrication
Category(s): Biotechnology
Targeted Cellular Ablation Based on the Morphology of Malignant Cells
The method presented herein can be utilized for the treatment of benign and malignant neoplasms. The mechanism of action is a purely physical treatment option that provides targeting killing options based on enlarged cellular nuclei, a reliable characteristic of malignant neoplasms. By tuning the parameters of a pulsed electric field treatment in silica...
Published: 9/21/2015   |   Inventor(s): Rafael Davalos, Scott Verbridge, Eduardo Latouche, Jill Ivey
Category(s): Medical