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Method for Controlling Cell Force and Shape for Gene Transfection
THE CHALLENGE
The main challenge in developing effective gene and drug delivery technologies lies in achieving high efficiency without compromising cell health, which is critical for commercial and clinical success. Current methods like viral vectors pose safety risks and non-viral carriers often have low uptake, while physical techniques lack scalability...
Published: 8/14/2025
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Inventor(s): Rafael Davalos, Amrinder Nain
Keywords(s):
Category(s): Technology Classifications > Electronics
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Microfluidic Collagen Assay for DEP-Isolated Tumor Subpopulations
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THE CHALLENGE
A major challenge in cancer diagnostics and drug development is the lack of an integrated, efficient system for isolating and testing the many different cell types found in tumor biopsies. Current methods are fragmented and labor-intensive, often requiring multiple manual steps like centrifugation and buffer exchange, which not...
Published: 8/14/2025
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Inventor(s): Temple Douglas, Rafael Davalos
Keywords(s):
Category(s): Technology Classifications > Engineering
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Wearable Microfluidic Pump for Continuous Transdermal Drug Delivery
THE CHALLENGE:
Continuous transdermal drug delivery is a critical area in biomedical engineering, particularly for managing chronic conditions such as diabetes, requiring the regular administration of medications like insulin. The demand for wearable, user-friendly devices that can provide consistent and reliable drug infusion is growing, driven by...
Published: 12/17/2024
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Inventor(s): Anne Staples, Rafael Davalos, Shuyu Zhang
Keywords(s):
Category(s): Technology Classifications > Biotechnology
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