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Programmed Innate Leukocytes as Potent Therapeutic Agents to Treat Atherosclerosis and Stroke

This invention discloses a novel strategy to reprogram either allogenic or heterologous peripheral blood neutrophils and/or monocytes with a selective compound in vitro, into a homeostatic state that is conducive for healing of coronary heart disease and/or stroke. Reprogrammed monocytes and/or neutrophils can be used through i.v. injection into human...

Published: 1/31/2024 | Inventor(s): Liwu Li, Shuo Geng, Yao Zhang

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Category(s): Technology Classifications > Biomedical

Enhanced Anti-Tumor Immune State

Challenge Similar to vaccines, traditional immunotherapies target specific epitopes of cancerous cells. While several immunotherapies offer several benefits over other alternatives, immunotherapies are not very effective because of several reasons. Given that microbes/cells have similar epitopes and that tumors mutate, therapy may not work in all cases...

Published: 1/31/2024 | Inventor(s): Liwu Li, Yao Zhang, Christina Lee

Keywords(s):

Category(s): Technology Classifications > Biomedical