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Human Carbohydrate Binding Protein for Modulation of Immune Responses
We have identified a putative receptor of the human innate immune system (expressed on lung epithelial cells and macrophages thus far) that binds to carbohydrate ligands such as chitin and potentially cellulose. We have shown that knocking down the gene for this receptor with siRNAs in lung epithelial cells in vitro results in dampening of the innate...
Published: 8/12/2014   |   Inventor(s): Christopher Lawrence, Brad Howard, Liwu Li
Category(s): Drug Discovery