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Organoid-Based Maturation of Liver Stem Cells
THE CHALLENGE
The field of regenerative medicine and drug development urgently requires reliable in vitro liver models that accurately mimic primary human hepatocyte functions. Primary hepatocytes, though ideal for studying liver physiology, suffer from limited availability and high inter-donor variability. Induced pluripotent stem cells (iPSCs) hold...
Published: 5/5/2025
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Inventor(s): Padmavathy Rajagopalan, Neeti Gandhi
Keywords(s):
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Biomedical
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Bouquet Fiber-based Neural Probe
THE PROBLEM
Neural probes are the key to unlocking the brain’s mysteries, yet current designs remain woefully inadequate. Most cutting-edge probes rely on outdated tip-based interactions, offering only a narrow, fragmented view of neural activity while leaving vast brain regions unexplored. Bulky, rigid structures provoke inflammation and tissue...
Published: 4/10/2025
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Inventor(s): Xiaoting Jia, Shan Jiang
Keywords(s):
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Electronics, Technology Classifications > Biotechnology, Technology Classifications > Biomedical
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Smart Exoskeleton Glove
THE CHALLENGE
Numerous diseases affect the mobility of the human hand including stroke, brachial plexus injury, arthritis, or carpal tunnel syndrome. In the United States, at least 1.1 million people report difficulty performing ordinary grasping operations, heavily reducing their economic outlook. In some cases, such as stroke, rehabilitation is possible...
Published: 4/10/2025
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Inventor(s): Raghuraj Chauhan, Oumar Barry
Keywords(s):
Category(s): Technology Classifications > Engineering, Technology Classifications > Biomedical, Technology Classifications > Medical Devices, Technology Classifications > Robotics
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An Assistive Robotic Exoskeleton Glove Designed for Patients with
Brachial Plexus Injuries
THE CHALLENGE
Exoskeleton gloves have proven to be invaluable in post-surgery therapy for patients with Brachial Plexus Injuries, countering hand muscle atrophy through controlled and assisted movements. While many rehab gloves target stroke recovery, they lack the desired Human-Machine Interface and struggle to find the right balance between performance...
Published: 11/12/2024
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Inventor(s): Pinhas Ben-Tzvi, Bijo Sebastian, Eric Refour
Keywords(s):
Category(s): Technology Classifications > Engineering, Technology Classifications > Biomedical, Technology Classifications > Biotechnology, Technology Classifications > Electronics, Technology Classifications > Medical Devices, Technology Classifications > Robotics
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Fiberoptic Microneedle Device for Convection-Enhanced Thermochemotherapy of Malignant Glioma
This invention allows diffuse convection-enhanced delivery of chemotherapy to tumors unreachable by direct surgical intervention. The device employs simultaneous co-delivery of fluid agents and laser energy at multiple infusion points to improve coverage of tumor margins. Previous similar methods have recently failed to meet clinical endpoints in Phase...
Published: 10/25/2023
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Inventor(s): Christopher Rylander, Robert Hood, John Robertson, Marissa Nichole Rylander
Keywords(s): Medical/Device
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Biomedical
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Photon-Integrating/Counting Detector Combination
THE CHALLENGE
Spectral computed tomography (CT) systems are a critical diagnostic tool in medicine. CT machines use computerized x-ray imaging to produce cross-sectional images of the body. Improvements in CT imaging technologies can lower radiation exposure and support life-saving interventions. Current spectral systems can be expensive to implement...
Published: 4/9/2025
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Inventor(s): Ge Wang, Jiyang Chu, Wenxiang Cong
Keywords(s):
Category(s): Technology Classifications > Biomedical, Technology Classifications > Medical Devices
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3D Printable Multifunctional Fibers
THE CHALLENGE
3D printing has enabled the customized production of many objects and devices, but that technology currently only creates passive units.
THE SOLUTION
Researchers at Virginia Tech have developed a coaxial micro-extrusion technique that enables us to take advantage of triboelectric energy generation and custom build sensors to fit anywhere....
Published: 11/6/2023
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Inventor(s): Blake Johnson, Yuxin Tong, John Robertson, Xiaoting Jia, Ziang Feng
Keywords(s):
Category(s): Technology Classifications > Engineering, Technology Classifications > Biotechnology, Technology Classifications > Biomedical, Technology Classifications > Energy, Technology Classifications > Additive Manufacturing, Technology Classifications > Electronics, Technology Classifications > Medical Devices
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