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SonicSurf Manipulator
THE CHALLENGE
Developing advanced contactless manipulation technologies lies in creating a solution that is not only technically effective but also scalable, affordable, and easy to integrate into real-world biomedical and chemical workflows. Current methods—like optical tweezers, magnetic actuators, and traditional acoustic systems—are...
Published: 5/13/2025
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Inventor(s): Zhenhua Tian, Teng Li, Jiali Li, Luyu Bo
Keywords(s):
Category(s): Technology Classifications > Biomedical, Technology Classifications > Chemicals/Materials, Technology Classifications > Engineering
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Washable SERS Fabrics via Micro-Imprinting
THE CHALLENGE
The major challenge in wearable SERS (Surface-Enhanced Raman Spectroscopy) sensors lies in bridging the gap between cutting-edge lab technology and real-world usability. While SERS offers powerful, label-free chemical detection at the molecular level, current fabrication methods rely on expensive clean-room processes, rigid substrates,...
Published: 5/9/2025
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Inventor(s): Aditya Garg, Wei Zhou
Keywords(s):
Category(s): Technology Classifications > Engineering, Technology Classifications > Biomedical
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Organoid-Based Maturation of Liver Stem Cells
THE CHALLENGE
The field of regenerative medicine and drug development urgently requires reliable in vitro liver models that accurately mimic primary human hepatocyte functions. Primary hepatocytes, though ideal for studying liver physiology, suffer from limited availability and high inter-donor variability. Induced pluripotent stem cells (iPSCs) hold...
Published: 5/5/2025
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Inventor(s): Padmavathy Rajagopalan, Neeti Gandhi
Keywords(s):
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Biomedical
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Fast Viral Detection via SERS and Machine Learning
THE CHALLENGE
The key challenge in developing effective virus detection tools for real-world environments lies in bridging the gap between laboratory-grade accuracy and field-ready usability. Current diagnostic methods like PCR and immunoassay are highly sensitive but depend on complex sample preparation, costly reagents, cold-chain logistics, and...
Published: 5/5/2025
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Inventor(s): Aditya Garg, Wei Zhou, Peter Vikesland, Linsey Marr, Nisha Duggal
Keywords(s):
Category(s): Technology Classifications > Biomedical, Technology Classifications > Engineering
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Serum-Free Media for Cell Culture
THE CHALLENGE
One of the biggest challenges facing the commercialization of cultivated meat is the heavy reliance on fetal bovine serum (FBS) in cell culture media—a component that is not only extremely expensive and ethically problematic, but also inconsistent due to its undefined and variable composition. FBS presents a major bottleneck to...
Published: 4/16/2025
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Inventor(s): Reza Ovissipour, Alexandrea Duscher, Inayat Batish
Keywords(s):
Category(s): Technology Classifications > Biomedical, Technology Classifications > Biotechnology
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Therapeutic Neutrophils for Cardiovascular Disease
THE CHALLENGE
Treating chronic inflammatory and cardiovascular diseases like atherosclerosis has proven difficult due to the lack of precision in current therapies. While these conditions are driven by complex immune responses, existing treatments rely heavily on broad, systemic anti-inflammatory drugs that often come with unwanted side effects and...
Published: 4/14/2025
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Inventor(s): Liwu Li, Shuo Geng
Keywords(s):
Category(s): Technology Classifications > Biomedical, Technology Classifications > Biotechnology, Technology Classifications > Pharmacology and Therapeutics
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Neutrophil Subsets for the Treatment of Cancer
THE CHALLENGE
Developing a cancer immunotherapy platform that can effectively and safely leverage the complex role of neutrophils—an abundant, yet highly variable, type of innate immune cell continues to prove challenging. Unlike current therapies that primarily target the adaptive immune system, an approach that must navigate the dual nature...
Published: 4/14/2025
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Inventor(s): Liwu Li, Yao Zhang
Keywords(s):
Category(s): Technology Classifications > Biomedical, Technology Classifications > Biotechnology, Technology Classifications > Pharmacology and Therapeutics
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Bouquet Fiber-based Neural Probe
THE PROBLEM
Neural probes are the key to unlocking the brain’s mysteries, yet current designs remain woefully inadequate. Most cutting-edge probes rely on outdated tip-based interactions, offering only a narrow, fragmented view of neural activity while leaving vast brain regions unexplored. Bulky, rigid structures provoke inflammation and tissue...
Published: 4/10/2025
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Inventor(s): Xiaoting Jia, Shan Jiang
Keywords(s):
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Electronics, Technology Classifications > Biotechnology, Technology Classifications > Biomedical
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Smart Exoskeleton Glove
THE CHALLENGE
Numerous diseases affect the mobility of the human hand including stroke, brachial plexus injury, arthritis, or carpal tunnel syndrome. In the United States, at least 1.1 million people report difficulty performing ordinary grasping operations, heavily reducing their economic outlook. In some cases, such as stroke, rehabilitation is possible...
Published: 4/10/2025
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Inventor(s): Raghuraj Chauhan, Oumar Barry
Keywords(s):
Category(s): Technology Classifications > Engineering, Technology Classifications > Biomedical, Technology Classifications > Medical Devices, Technology Classifications > Robotics
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Intensity-adjustable Cavitation Generator
THE CHALLENGE
Water treatment of large volumes of liquids is a critical aspect of many industrial processes, notably in the chemical, food, and pharmaceutical industries. With energy costs rapidly rising, it is highly desirable to improve the treatment efficiencies and adaptiveness with lower energy consumption.
OUR SOLUTION
Hydrodynamic cavitation...
Published: 4/4/2025
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Inventor(s): Mingming Ge, Olivier Coutier-Delgosha
Keywords(s):
Category(s): Technology Classifications > Biotechnology, Technology Classifications > Chemicals/Materials, Technology Classifications > Environment/Green Tech, Technology Classifications > Mining and Recycling, Technology Classifications > Biomedical
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