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Serum-Free Media for Cell Culture
THE CHALLENGE
One of the biggest challenges facing the commercialization of cultivated meat is the heavy reliance on fetal bovine serum (FBS) in cell culture media—a component that is not only extremely expensive and ethically problematic, but also inconsistent due to its undefined and variable composition. FBS presents a major bottleneck to...
Published: 4/16/2025
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Inventor(s): Reza Ovissipour, Alexandrea Duscher, Inayat Batish
Keywords(s):
Category(s): Technology Classifications > Biomedical, Technology Classifications > Biotechnology
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Therapeutic Neutrophils for Cardiovascular Disease
THE CHALLENGE
Treating chronic inflammatory and cardiovascular diseases like atherosclerosis has proven difficult due to the lack of precision in current therapies. While these conditions are driven by complex immune responses, existing treatments rely heavily on broad, systemic anti-inflammatory drugs that often come with unwanted side effects and...
Published: 4/14/2025
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Inventor(s): Liwu Li, Shuo Geng
Keywords(s):
Category(s): Technology Classifications > Biomedical, Technology Classifications > Biotechnology, Technology Classifications > Pharmacology and Therapeutics
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Neutrophil Subsets for the Treatment of Cancer
THE CHALLENGE
Developing a cancer immunotherapy platform that can effectively and safely leverage the complex role of neutrophils—an abundant, yet highly variable, type of innate immune cell continues to prove challenging. Unlike current therapies that primarily target the adaptive immune system, an approach that must navigate the dual nature...
Published: 4/14/2025
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Inventor(s): Liwu Li, Yao Zhang
Keywords(s):
Category(s): Technology Classifications > Biomedical, Technology Classifications > Biotechnology, Technology Classifications > Pharmacology and Therapeutics
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Bouquet Fiber-based Neural Probe
THE PROBLEM
Neural probes are the key to unlocking the brain’s mysteries, yet current designs remain woefully inadequate. Most cutting-edge probes rely on outdated tip-based interactions, offering only a narrow, fragmented view of neural activity while leaving vast brain regions unexplored. Bulky, rigid structures provoke inflammation and tissue...
Published: 4/10/2025
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Inventor(s): Xiaoting Jia, Shan Jiang
Keywords(s):
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Electronics, Technology Classifications > Biotechnology, Technology Classifications > Biomedical
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Intensity-adjustable Cavitation Generator
THE CHALLENGE
Water treatment of large volumes of liquids is a critical aspect of many industrial processes, notably in the chemical, food, and pharmaceutical industries. With energy costs rapidly rising, it is highly desirable to improve the treatment efficiencies and adaptiveness with lower energy consumption.
OUR SOLUTION
Hydrodynamic cavitation...
Published: 4/4/2025
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Inventor(s): Mingming Ge, Olivier Coutier-Delgosha
Keywords(s):
Category(s): Technology Classifications > Biotechnology, Technology Classifications > Chemicals/Materials, Technology Classifications > Environment/Green Tech, Technology Classifications > Mining and Recycling, Technology Classifications > Biomedical
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Wearable Microfluidic Pump for Continuous Transdermal Drug Delivery
THE CHALLENGE:
Continuous transdermal drug delivery is a critical area in biomedical engineering, particularly for managing chronic conditions such as diabetes, requiring the regular administration of medications like insulin. The demand for wearable, user-friendly devices that can provide consistent and reliable drug infusion is growing, driven by...
Published: 12/17/2024
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Inventor(s): Anne Staples, Rafael Davalos, Shuyu Zhang
Keywords(s):
Category(s): Technology Classifications > Biotechnology
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Formulation of Iron Oxide Nanoparticle Suspensions for FUS/MRI Applications
Focused ultrasound combined with magnetic resonance imaging (FUS/MRI) is a promising approach for noninvasive therapy that requires precise imaging of tissue using MRI to guide the FUS process. The MRI suffers from interference from water baths commonly used to transmit the focused ultrasound waves from a transmitter to the tissue. In this work, iron...
Published: 12/20/2023
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Inventor(s): Richey Davis, Austin Fergusson, Eli Vlaisavljevich, Connor Edsall, Craig Meyer, Steven Allen
Keywords(s):
Category(s): Technology Classifications > Biomedical, Technology Classifications > Biotechnology
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An Assistive Robotic Exoskeleton Glove Designed for Patients with
Brachial Plexus Injuries
THE CHALLENGE
Exoskeleton gloves have proven to be invaluable in post-surgery therapy for patients with Brachial Plexus Injuries, countering hand muscle atrophy through controlled and assisted movements. While many rehab gloves target stroke recovery, they lack the desired Human-Machine Interface and struggle to find the right balance between performance...
Published: 11/12/2024
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Inventor(s): Pinhas Ben-Tzvi, Bijo Sebastian, Eric Refour
Keywords(s):
Category(s): Technology Classifications > Engineering, Technology Classifications > Biomedical, Technology Classifications > Biotechnology, Technology Classifications > Electronics, Technology Classifications > Medical Devices, Technology Classifications > Robotics
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Transparent NanoplasmonicMeshes for
Bio-interfaced Multimodal Biochemical Sensing
THE CHALLENGE
For multicellular systems such as microbial biofilms and tumors it is essential to capture the holistic system-level spatiotemporal picture. This allows for the understanding of complex and dynamically evolving biological activities to determine effective therapeutic intervention methods. Currently, standard bioanalysis methods do not...
Published: 2/1/2024
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Inventor(s): Aditya Garg, Wei Zhou, Elieser Mejia
Keywords(s):
Category(s): Technology Classifications > Chemicals/Materials, Technology Classifications, Technology Classifications > Biotechnology
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Nanoparticle-based Nicotine Nanovaccine
THE CHALLENGE:
Tobacco smoking is one of the largest public health threats the world has ever faced and results in over seven million deaths annually world wide. Smoking cessation is a difficult and largely unsuccessful undertaking; only 3-5% of unassisted smokers are able to remain abstinent for more than six months, and the use of pharmacological...
Published: 7/15/2024
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Inventor(s): Chenming (mike) Zhang, Zongmin Zhao
Keywords(s):
Category(s): Technology Classifications > Biomedical, Technology Classifications > Biotechnology, Technology Classifications > Pharmacology and Therapeutics
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